Due to the fact that CBD makes people sleepy on its own, it also intensifies the effects of other drugs like alcohol, benzodiazepines, antipsychotics, antidepressants, and opioids, as well as dietary supplements like kava, melatonin, and St. John’s Wort. These drugs include antihistamines like Benadryl, benzodiazepines like Xanax, Ativan, or Valium, antipsychotics, and
What supplements does CBD interfere with?
CBD might cause sleepiness and slowed breathing. Taking it along with other supplements with similar effects might cause too much sleepiness and/or slowed breathing in some people. Examples of supplements with this effect include hops, kava, L-tryptophan, melatonin, and valerian.
What medications react badly with CBD oil?
In addition, CBD could potentially interact with naproxen, tramadol, celecoxib, etoricoxib, fluoxetine, and tofacitinib as these are metabolized in the liver by cytochrome P450 enzymes.